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Fig. 3 | BMC Evolutionary Biology

Fig. 3

From: Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish

Fig. 3

Putative PPREs in the zebrafish fabp1a, fabp1b.1 and fabp1b.2, and spotted gar fabp1 gene promoters. Putative PPREs were identified using MatInspector (v. 8.1). Approximately 3,000 bp promoter fragments are shown (scale: bars at 500 bp intervals). Right-facing arrows indicate the TSS. Gene name is indicated to the left of each promoter. Coloured rectangles indicate putative PPREs (sequence, position relative to TSS, and % sequence identity to the defined vertebrate PPRE consensus sequence below each promoter). Purple rectangles indicate PPREs that may be PPARα-selective. Red rectangles indicate PPREs that may be PPARγ-selective. Blue boxes indicate the 5′FR. Orange boxes indicate the DR1. A possible PPARα-selective PPRE was identified at −2,710 bp relative to the TSS of the zebrafish fabp1a promoter. A possible PPARγ-selective PPRE was identified at −1,232 bp relative to the TSS of the zebrafish fabp1b.1 promoter. No PPREs were identified in the zebrafish fabp1b.2 promoter. Two putative PPREs were identified at −1,953 bp (PPRE-1) and −539 bp (PPRE-2) relative to the TSS of the spotted gar fabp1 promoter that were PPARα- and PPARγ-selective, respectively. Complete sequence data are provided in Additional file 1

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