WY14643 | ||||||
Upward Slope | Downward Slope | |||||
- | GW6471 | T0070907 | - | GW6471 | T0070907 | |
E max (RLU) | 80.6 ± 7.40 | 97.5 ± 3.78 | 74.2 ± 9.63 | - | - | - |
E min (RLU) | 10.9 ± 4.64 | 8.86 ± 3.50 | 8.93 ± 4.72 | 24.7 ± 4.88** | - | 21.6 ± 4.13** |
EC50 (μM) | 0.12 (0.07–0.28) | 0.54 (0.43–0.65)* | 0.17 (0.05–0.25) | 0.69 (0.52–1.1)** | – | 0.45 (0.22–0.71)** |
Rosiglitazone | ||||||
Upward Slope | Downward Slope | |||||
- | GW6471 | T0070907 | - | GW6471 | T0070907 | |
E max (RLU) | 56.3 ± 2.40 | 57.4 ± 2.44 | 42.5 ± 4.50 | - | - | - |
E min (RLU) | 5.28 ± 4.80 | −0.42 ± 2.73 | 1.21 ± 7.80 | - | - | - |
EC50 (μM) | 0.009 (0.006–0.017) | 0.016 (0.012–0.021) | 0.024 (0.021–0.062)* | - | - | - |