Fig. 3From: Metabolic modelling in a dynamic evolutionary framework predicts adaptive diversification of bacteria in a long-term evolution experimentSimulated and experimental dynamics of population density and substrate concentrations. a Simulated dynamics over a 24-h transfer cycle for the evolved acetate specialist (left, ID: 44490), ancestral (middle, ID: 1), and evolved glucose specialist (right, ID: 12364) model organisms. Model IDs are the same as in Fig. 1b. b Experimental data for the 6.5KS1 (left), ancestral (middle), and 6.5KL4 (right) clones from the LTEE. Biological experiments were performed at a 10-fold higher concentration of glucose than the simulations to increase cell density and thereby improve the accuracy of the measurements of cell growth and concentrations of residual glucose and secreted acetate. Biological data are means of three replicate cultures and error bars show standard deviationsBack to article page