Fig. 7From: Ancient recombination events and the origins of hepatitis E virusHEV GI capsid (ORF2) viral homologues. Selected homologous viral sequences to the HEV capsid protein, identified using tBlastn search. Homologues are organized into color-coded viral families. Shading as in Fig. 3. The HEV main capsid structural regions are illustrated above, to show regions of the HEV capsid with poor or no homologous sequence. S = shell domain; M = intermediate domain; P = protruding domain. The N (arginine/proline rich signal sequence) and C-terminal 52 amino acids of the protein sequence are absent in the mature capsid, as indicated by the red arrows [after Dryden et al. [60]]Back to article page