Phylogenetic analyses reveal molecular signatures associated with functional divergence among Subtilisin like Serine Proteases are linked to lifestyle transitions in Hypocreales

Table 1 Likelihood estimates of Subtilisin (S08.005) gene family for site models in PAML

Model	np	Parameter estimates (Proportion p, omega ω)	lnL	LRT pairs	df	2ΔlnL	P	Positively selected sites (BEB)
site model
M0:one ratio	106	ω = 0.13223	−28649.08	M0/M3	4	0	1
Model M3:Discrete	110	p ₀ = 0.00000	−28649.08
		p ₁ = 0.00000
		p ₂ = 1.00000
		ω ₀ = 0.00000
		ω₁ = 0.00000
		ω₂ = 0.13223
M1a(neutral)	107	p ₀ = 0.00001	−30002.75	M1a/M2a	2	86.44	0.00
		p ₁ = 0.99999
		ω₀ = 0.00001
		ω₁ = 1.00000
Model 2a: Positive Selection	109	p ₀ = 0.00000	−29959.53					4D,5Q,160S,187G
		p ₁ = 0.87583
		p ₂ = 0.12417,
		ω ₀ = 0.00000
		ω₁ = 1.00000
		ω ₂ = 2.09472
Model 7: beta	107	p = 2.04966	−28245.05	M7/M8	2	3515.4	0.00
Model 7: beta	107	q = 9.83402	−28245.05	M7/M8	2	3515.4	0.00
Model 8 :	109	p ₀ = 0.00001	−30002.75
		p = 0.00500
		q = 1.23069
		p ₁ = 0.99999
		ω = 1.00000

Selection analysis by site models. np: number of free parameters. lnL: log likelihood. LRT: likelihood ratio test. df: degrees of freedom. 2∆lnL: twice the log-likelihood difference of the models compared. The significant tests at 95 % cut off are labeled with*. Bold: P < 0.05

ISSN: 2730-7182