Fig. 1

Occurrence of EC subdivisions in PM* and SM* and their overrepresentation in BGCs. a A plot of f _PM *(EC_sd) -values versus f _SM *(EC_sd) -values. These are the normalized frequencies for the occurrence of EC subdivisions in the datasets enzymes _PM* and enzymes _SM* , respectively. b A plot of overrep(EC_sd)-values versus f _SM *(EC_sd) -values. Each overrep(EC_sd)-value is the ratio f _SM *(EC_sd)/f _PM *(EC_sd) that relates the abundance of a subdivision in enzymes _PM* and enzymes _SM* . For subdivisions with an overrep()-value > 20 (red symbols) and those most abundant in enzymes _SM* (green symbols), the EC_sd number is given