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Table 6 Annotation of the ±10 genomic neighborhood of Sare_3902 from S. arenicola (strain CNS-205)

From: Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism

BGC0000333; SM* saq:Sare_4569 4-oxalocrotonate decarboxylase (EC 4.1.1.77) ↔ PM saq:Sare_3902; E-value 4.0E-47

E_PM

K_SM

KEGG Annotation

Pathways in ±10/±2 Nh

  

saq:Sare_3892 aminopeptidase N (EC 3.4.11.2)

8/2 saq00380 Tryptophan metabolism

6/4 saq01120 Microbial metabolism in diverse environments

5/4 saq00622 Xylene degradation

5/4 saq00362 Benzoate degradation

5/4 saq01220 Degradation of aromatic compounds

4/3 saq00360 Phenylalanine metabolism

4/3 saq00621 Dioxin degradation

1/0 saq00643 Styrene degradation

1/0 saq00330 Arginine and proline metabolism

1/1 saq00620 Pyruvate metabolism

1/1 saq00650 Butanoate metabolism

1/0 saq00480 Glutathione metabolism

1/0 saq00627 Aminobenzoate degradation

  

saq:Sare_3893 conserved hypothetical protein

  

saq:Sare_3894 conserved hypothetical protein

P

 

saq:Sare_3895 Amidase; K01426 amidase (EC 3.5.1.4)

  

saq:Sare_3896 amidohydrolase 2 (EC 4.1.1.45)

  

saq:Sare_3897 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6)

  

saq:Sare_3898 Endoribonuclease L-PSP (EC 3.5.99.5)

P

 

saq:Sare_3899 4-oxalocrotonate decarboxylase (EC 4.1.1.77)

P

 

saq:Sare_3900 pyruvate carboxyltransferase

P

 

saq:Sare_3901 Acetaldehyde dehydrogenase

P

 

saq:Sare_3902 4-oxalocrotonate decarboxylase (EC 4.1.1.77)

  

saq:Sare_3903 aldehyde dehydrogenase

  

saq:Sare_3904 Kynurenine 3-monooxygenase (EC 1.14.13.9)

P

 

saq:Sare_3905 kynureninase; K01556 kynureninase (EC 3.7.1.3)

  

saq:Sare_3906 tryptophan 23-dioxygenase

  

saq:Sare_3907 transcriptional regulator

  

saq:Sare_3908 conserved hypothetical protein

  

saq:Sare_3909 peptidase C60 sortase A and B

  

saq:Sare_3910 HNH endonuclease

  

saq:Sare_3911 MscS Mechanosensitive ion channel

  

saq:Sare_3912 major facilitator superfamily MFS_1

  1. The first line gives the name of the MIBiG cluster containing the considered SM* enzyme, the annotation of the SM* and the related putative PM enzyme from the same genome, and the BLAST E-value resulting from the comparison of the corresponding two protein sequences
  2. The following lines characterize the ±10 genomic neighbourhood of the putative PM enzyme. A “P” in column “E_PM” indicates that this enzyme function, i. e. EC number, occurs in enzymes PM* and an “S” in column “K_SM” indicates that KEGG assigned this enzyme function to the pathway “Biosynthesis of secondary metabolites”. The column named “KEGG Annotation” lists KEGG-ID, function and EC number of the gene products. The column named “Pathways in ±10/±2 Nh” lists the number of genes from the corresponding two neighborhoods of the putative PM enzyme that belong to the listed KEGG pathways. For this table, the gene annotations taken from the respective html-page were shortened for the sake of brevity