Table 1 Parameter estimates for PAML models across TLR genes

TLR5

M7 (β)

M8 (β & ω)

p = 0.17, q = 0.26

p = 0.24, q = 0.45, f₀ = 0.94

ω = 2.68, f₁ = 0.06

31, L,96.1; 63,T, 97.4; 102,G, 96.3; 165,R, 97.1; 419,P, 97.36;

56, T,95.7

LR4

M7 (β)

M8 (β & ω)

p = 0.05, q = 0.04

p = 0.23, q = 0.38, f₀ = 0.90

ω = 2.59, f₁ = 0.10

293,D,99.3; 297,A, 99.9; 318,S, 97.9; 320,E, 98.0; 336,V, 96.1; 340,V, 99.4; 362,V, 99.3; 369,F, 97.6; 370,V, 97.5; 414,V, 99.1; 499,V, 99.2; 513,T, 95.2; 832,N, 97.1;

TLR2

M7 (β)

M8 (β & ω)

p = 0.14, q = 0.24

p = 0.22, q = 0.43, f₀ = 0.96

ω = 2.55, f₁ = 0.04

765, M, 98.4

TLR3

M7 (β)M8 (β & ω)

p = 0.19, q = 0.35

p = 0.28, q = 0.75, f₀ = 0.98ω = 2.71, f₁ = 0.02

4, H, 98.3; 277, V, 96.9; 382, F, 97.3

TLR7

M7 (β)

M8 (β & ω)

p = 0.03, q = 0.07

p = 0.15, q = 0.59, f₀ = 0.95

ω = 2.23, f₁ = 0.05

100,I,97.4; 161,L,96.6; 282,I,96.5; 393,R,97.2; 461,A,95.5; 566,H,98.5; 667,L,98.8; 693,G,97.6; 697,N,96.9; 723,H,97.5; 776,N,97.1

TLR9

M7 (β)

M8 (β & ω)

p = 0.13, q = 0.53

p = 0.17, q = 1.44, f₀ = 0.93

ω = 1.72, f₁ = 0.07

693,R,95.5; 722,K,95.7

TLR10

M7 (β)

M8 (β & ω)

p = 0.19, q = 0.24

p = 0.35, q = 0.57, f₀ = 0.94

ω = 2.28, f₁ = 0.06

611, G, 97.1