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Fig. 4 | BMC Evolutionary Biology

Fig. 4

From: Transcriptomic insights into the genetic basis of mammalian limb diversity

Fig. 4

Conservation of gene expression profiles. The conservation of the gene expression profiles of all study species (bat, mouse, opossum, and pig) across embryonic development of the fore- (a) and hind limb (b), as determined by the mean of all species pairwise Spearman coefficients (X axis). Results for the ridge stage are shown in red, for the bud stage in green, and for the paddle stage in blue. To test the robustness of differences in Spearman coefficients with respect to the gene selection, we randomly sub-sampled gene sets at intensities ranging from 50 to 100% of all genes (Y axis). In the box plots, the bottom and top of the boxes represent the first and third quartiles of the data, and the line through the middle of the box the second quartile (median). The whiskers range from the 2nd to 98th percentiles, and the open circles depict the outliers to these percentiles

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