Fig. 4From: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune responseSLPs differentially modulate cell surface marker expression on macrophages. J774 macrophages were stimulated with SLP from ribotypes 001, 014, 027 and 078 (20 μg/mL) for 24 h. LPS (100 ng/mL) was used as a positive control. Results show expression of the cell surface markers CD80 and CD86. Control cells are shaded in grey, SLP-stimulated cells are labelled in blue, and LPS-stimulated cells are labelled in redBack to article page