Characterizing the roles of changing population size and selection on the evolution of flux control in metabolic pathways

Table 3 A statistical analysis is presented to evaluate the role of adaptation in driving inter-molecular vs. intra-molecular patterns of co-evolution

	Slope estimate	Standard error	p-value
Count	0.04227	0.0237	0.0424
Ratio	0.00326	0.00811	0.3264

Clusters that reflect co-evolving parameters were evaluated in cluster count and in the ratio of the inter- to intra-molecular clusters observed over different periods in Fig. 1. This was done, both during periods of adaptation and with an observation of a lag period for a response. Slope estimates are the main effect from the mixed-effects regression analyses, and standard errors are estimated based on the null distribution of slopes generated by the permutation test. The p-values were obtained by counting the proportion of the generated null distribution that was greater than the slope estimates

ISSN: 2730-7182