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Table 2 False Positive Rates (FPR) for different conditions and posterior probability thresholds under model M1 and M2

From: Detecting consistent patterns of directional adaptation using differential selection codon models

  M1 M2
Threshold Mean number of FP FPR Mean number of FP FPR
Condition 1 (within-patients)
 >0.55 1843.7 20.8 1845.8 20.8
 >0.60 1112.7 12.6 1166.8 13.2
 >0.65 684.9 7.7 737.8 8.3
 >0.70 316.9 3.6 334.5 3.8
 >0.75 173.1 2.0 181.8 2.1
 >0.80 81.8 0.9 86.5 1.0
 >0.85 26.0 0.3 31.7 0.4
 >0.90 7.1 0.1 4.6 0.1
 >0.95 0.75 0.01 0.1 0.0
Condition 2 (HLA-B57+)
 >0.55 1004.1 11.3 957 10.8
 >0.60 456.3 5.15 471 5.3
 >0.65 229 2.58 237.1 2.7
 >0.70 88.9 1 78.7 0.9
 >0.75 31.3 0.3 27.3 0.3
 >0.80 12.9 0.15 8.4 0.1
 >0.85 3.8 0.04 1.6 0.02
 >0.90 0.4 0 0.05 0
 >0.95 0 0 0 0
Condition 3 (HLA-B35+)
 >0.55 1245.1 14 1226.5 13.8
 >0.60 632.4 7.1 683 7.7
 >0.65 345.6 3.9 385.3 4.3
 >0.70 141.4 1.6 148.1 1.7
 >0.75 58.6 0.7 64.4 0.73
 >0.80 25.3 0.3 23.1 0.3
 >0.85 7.7 0.1 6.5 0.07
 >0.90 1.2 0.01 0.9 0.01
 >0.95 0 0 0 0