Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Fig. 1 | BMC Evolutionary Biology

Fig. 1

From: Evolutionary origin of type IV classical cadherins in arthropods

Fig. 1

Genomic and domain organization of classical cadherins in Parasteatoda tepidariorum and Strigamia maritima. a. Schematic representation of exons (upper), transcripts (middle), and domain organization (lower) of Pt1-, Pt2-, Sm1-, and Sm2- cadherins, compared with those of DE- and DN-cadherins. The scale bar indicates 1 Kbp. All exons identified in the genome sequences are depicted in blue, except for the exons depicted in gray for the Sm2-cadherin gene, which remained hypothetical because its sequence was not found in the S. maritima genome sequence assembly. For each cadherin, the exons are tentatively numbered to facilitate comparison (numbers in blue). The coding region of each transcript is depicted in orange, with the 5’- and 3’-untranslated regions depicted in gray. The domain names are abbreviated as follows: EC, extracellular cadherin domain; NC, non-chordate classical cadherin domain; CE, cysteine-rich EGF-like domain; LG, laminin globular-like domain; TM, transmembrane domain; CP, cytoplasmic domain. b. Schematic representation of the genomic organization of the Pt1-, Pt2-, Sm1-, and Sm2-cadherin genes, compared with those of the DN- and DE-cadherin genes. Thin horizontal black lines indicate the genome sequences. The scale bar indicates 100 Kbp. Blue triangles indicate individual exons, which are numbered to facilitate comparison. Red lines indicate scaffold sequences of the P. tepidariorum or S. maritima genome assemblies. Broken lines indicate missing sequences. Conserved insertions of the largest introns observed in the Pt1-, Pt2-, DN-, and Sm2-cadherin genes are indicated by asterisks in both A and B. The genomic sequences annotated for the Pt1- and Pt2-cadherins are available in GenBank (BR001342 and BR001343)

Back to article page