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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Evolution of the p53-MDM2 pathway

Fig. 2

a Phylogenetic tree based on multiple sequence alignment of the p53/p63/p73 protein family only including species with the TAD. The evolutionary relations are the same as what is generally accepted regarding species evolution and whole genome duplications. The Placozoa sequence is most distantly related to all the other genes in the tree and was therefore used as an outgroup. b Phylogenetic tree based on multiple sequence alignment of the MDM protein family only including species with the p53/p63/p73BD. The evolutionary relations are the same as what is generally accepted regarding species evolution and whole genome duplications. The Placozoa sequence is most distantly related to all the other genes in the tree and was therefore used as an outgroup

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