Skip to main content
Fig. 4 | BMC Evolutionary Biology

Fig. 4

From: Evolution of the p53-MDM2 pathway

Fig. 4

a Crystal structure of the complex between mouse p53 TAD (red) and the p53/p63/p73BD of MDM2 (blue) (PDB entry: 1YCR) [37]. The residues in p53 TAD shown as sticks are the three conserved residues in the FxxxWxxL motif. b Alignment of the TAD of selected species. Amino acid numbering and phosphorylation sites are according to human p53. Agadir prediction [39] of the helical propensity in percent is shown beside the alignment for the different species. The color-coding is according to eBioX alignment tool

Back to article page