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Table 1 Description of the wild house mice populations used in this study

From: Evaluating the maintenance of disease-associated variation at the blood group-related gene B4galnt2 in house mice

Population

Species

Location

Study

Sample Size

RIIIS/J Allele Frequency

Hardy-Weinberg

ID

Group

RR

RC

CC

Total

 DE

A

Mmd

Cologne-Bohn (DE)

i

0

0

36

36

0.00

Equilibrium

 CB

A

Mmd

Cologne-Bohn (DE)

iii

0

0

15

15

0.00

Equilibrium

 DB

A

Mmd

Divonne-lès-Bains (FR)

iii

0

1

11

12

0.04

Equilibrium

 LO

A

Mmd

Louan-Villegruis-Fontaine (FR)

iii

0

0

12

12

0.00

Equilibrium

 NA

A

Mmd

Nancy (FR)

iii

0

0

12

12

0.00

Equilibrium

 SL

A

Mmd

Schömberg (DE)

iii

0

1

11

12

0.04

Equilibrium

Overall

A

--

--

--

0

2

97

99

0.01

Equilibrium

 MC

B

Mmd

Massif Central (FR)

iii

1

11

7

19

0.34

Equilibrium

 ES

B

Mmd

Espelette (FR)

iii

3

10

9

22

0.36

Equilibrium

 AN

B

Mmd

Anger (FR)

iii

4

8

6

18

0.44

Equilibrium

 CH

B

Mmd

Chicago (USA)

i

1

3

6

10

0.25

Equilibrium

 CA

B

Mmd

Cameroon

i

2

18

9

29

0.38

Equilibrium

 FR

B

Mmd

Massif Central (FR)

i

12

16

22

50

0.40

Homozygotes Excess

Overall

B

--

--

--

23

66

59

148

0.38

Equilibrium

 IR

C

Mmd

Iran

ii

10

5

2

17

0.74

Equilibrium

 SP

C

Ms

Spain

ii

19

7

1

27

0.83

Equilibrium

Overall

C

--

--

--

29

12

3

44

0.80

Equilibrium

  1. Data from populations belonging to Mus musculus domesticus (Mmd) or Mus spretus (Ms) were included from (i) Johnsen et al. 2009 [4], (ii) Linnenbrink et al. 2011 [5] and (iii) Linnenbrink 2013 et al. [18]. The populations are categorized into three groups: A) populations with low RIIIS/J allele frequency, suspected to be in a non-pathogenic environment, B) populations with intermediate RIIIS/J allele frequency, suspected to be in a pathogenic environment and C) populations with high frequency of a modified RIIIS/J allele assumed to carry no bleeding cost, and suspected to be in a pathogenic environment. The sample size is given with the number of individuals of each genotype (RR for RIIIS/J homozygotes, CC for C57BL/6 J homozygotes and RC for heterozygotes), and the total number of mice. The corresponding RIIIS/J allele frequency and whether the population significantly deviates from HWE are also indicated