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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Phylogenomics of Cas4 family nucleases

Fig. 2

Representation of different Cas4 groups in archaea and bacteria. a. Presence and absence of CAS-Cas4 and Cas4 solo in completely sequenced genomes of archaea and bacteria. Individual genomes were assigned weights inversely proportional to the number of genomes from each species; the presence fraction was calculated with genome weights taken into account (see Additional file 4: File S2). b. Numbers of species in the complete data set containing Cas4 from different CRISPR-Cas4 subtypes and Cas4 solo. The counts were obtained from the complete set of CAS-Cas4 and Cas4-solo (5571 and 702, respectively). Only one strain per species was counted for each respective category of Cas4 assignments to avoid sequencing bias. See Additional file 7: Table S1 for details. Abbreviation: AM, stand-alone adaptation module

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