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Fig. 4 | BMC Evolutionary Biology

Fig. 4

From: Phylogenomics of Cas4 family nucleases

Fig. 4

Selected examples of in situ replacement of effector complex genes in CRISPR-Cas systems of different subtypes. For each locus, species name, genome accession number and the respective nucleotide coordinates are indicated. The genes of a representative locus are shown by arrows. The arrow indicates the transcription direction of the respective gene. Genes and CRISPR arrays are shown roughly to scale. Homologous genes are connected by dotted lines and amino acid sequence identity (%) is indicated. Asterisks indicate cases where the overall sequence identity was very low, and the percent identity was taken from a small aligned fragment. Cas4 genes are shown in green. The region of likely in situ replacement is shown by a blue rectangle

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