Fig. 1

The network presenting data on pairwise interactions involving TBEV (or viral RNA and protein) and 140 human genes/proteins from the TBEVHostDB. The descriptions of genes/proteins datasets were given in Table 1. The descriptions of interactions were given in Table 2. The names of 39 genes/proteins from up- or down-regulated dataset that were revealed from studies comparing TBEV-infected and uninfected human sera or other human biological samples (presented in Table 3) are shown in blue. Hexagons denote 20 proteins revealed to be up- or down-regulated in human sera, plasma, and blood