Fig. 2

Consensus maximum likelihood phylogeny of UDP-glycosyltransferases nucleotide sequences from Leishmaniinae. The phylogeny was estimated with PHYML with a GTR+Γ model and 500 bootstrap replicates. Terminal nodes are named with Tritrypdb [46] identifiers; internal nodes are labeled with bootstrap percentages for maximum likelihood (ML), posterior probabilities (BI), and logdet (NJ) methods for nucleotides sequences and with bootstrap percentages for ML (PhyML [51]), posterior probabilities (BI), and bootstrap percentages for ML (IQTree [53]) for protein sequences. Dashes represent differences in topology. Tree is rooted with Angomonas deanei and Strigomonas culicis as outgroup. The gray star indicates a gene loss in L. mexicana and L. braziliensis after the gene transposition event to chromosome 14. Tips are labeled according to key. Clades are identified as SCG, SCGR, and SCGL according to previous annotation in L. major (Dobson et al., 2006). Available expression data is represented as log2 fold change of amastigote (AMA), constitutive (C), or promastigotes (PRO) in a heat map according to study reference. Asterisk indicates data is transcriptomic. Refer to text for labels i to iv