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Table 3 Gene set enrichment analysis based on Fisher’s exact test with Yate’s continuity correction

From: The evolution of a series of behavioral traits is associated with autism-risk genes in cavefish

Divergence metrics

Comparisons

Significant ASD genes

Total ASD genes

Significant genes in genome

Total genes in genome

Yate’s Chi Square X2

Degrees of freedom

Yate’s P-value

hapFLK

Whole genome

86

635a

1648

22,710

34.557

1

< 0.0001

  1. Gene enrichment for ASD genes was based on comparisons between Choy surface (Choy) and Cave (Pachón). Calculations were performed using the chisq.test function in R
  2. aNote that total ASD genes for hapFLK is lower than the total for orthologs and paralogs due to missing data