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Fig. 6 | BMC Evolutionary Biology

Fig. 6

From: Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences

Fig. 6

Gains of additional expression in other tissues in a phylogenetic context. The population from IRA represents the stem population for GER and FRA, which have separated about 3000 years ago. The figure depicts the analysis where we ask two different questions for each of the tissue specific INT transcripts of the IRA population. First, we ask for each of the tissues in IRA whether they gained a new transcript in GER or FRA in any other tissue. These numbers and percentages are presented in the left tables, labeled as “gained” (the top table is for GER, the bottom table for FRA). Here we find that transcripts initially expressed only in thymus, spleen, lung and brain in IRA have the highest percentage of gained transcripts in any other tissue in GER or FRA. Second, we ask which of the tissues in GER or FRA receive the additional expressions. These are the tables to the right, labeled as “received” (the top table is for GER, the bottom table for FRA). Here we find that lung, spleen and thymus are the tissues that receive additional expression from any of the IRA tissues. The tables present absolute numbers and the percentages for each tissue, scaled according to the total number of INT transcripts found in the respective tissue (left) and the total number of gains (right). The ranking of the tissues is according to this percentage value

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