Table 3 Codon-based tests of positive selection. A summary of P-values and posterior probabilities obtained for selection tests are shown for those codons where at least one test resulted with significant value after FDR correction (global α = 0.05). The codon location in domains (Cyto, trans or extr) is indicated for each codon under positive selection. Biochemical properties significantly associated with amino acid sites under selection are indicated for PRIME test (See Methods for abbreviations)
Gene/Codon | Domain | codeml BEB | SLAC | FEL | IFEL | REL | MEME | FUBAR | PRIME |
|---|---|---|---|---|---|---|---|---|---|
Gr63a | |||||||||
 73 | Cyto | 0.571 | 0.471 | 0.369 | > 0.050 | 0.980 | 0.227 | 0.732 | > 0.050 |
 93 | Cyto | < 0.500 | 0.748 | 0.642 | > 0.050 | 0.955 | 0.487 | 0.650 | > 0.050 |
 482 | Extr | 0.977 | 0.189 | 0.184 | > 0.050 | 0.990 | 0.078 | 0.941 | V |
 485 | Extr | 0.906 | 0.428 | 0.434 | > 0.050 | 0.986 | 0.139 | 0.906 | H |
Or67c | |||||||||
 100 | Trans | < 0.500 | 0.132 | 0.092 | > 0.050 | 0.933 | 0.141 | 0.648 | > 0.050 |
 116 | Cyto | < 0.500 | 0.982 | 0.815 | > 0.050 | 0.807 | 0.583 | 0.401 | > 0.050 |
 125 | Cyto | < 0.500 | 0.752 | 0.529 | > 0.050 | 0.866 | 0.449 | 0.467 | > 0.050 |
 236 | Cyto | < 0.500 | 0.199 | 0.348 | > 0.050 | 0.901 | 0.023 | 0.653 | S |
 253 | Cyto | 0.998 | 0.237 | 0.029 | > 0.050 | 0.976 | 0.058 | 0.906 | C, VR |
 274 | Cyto | < 0.500 | 0.434 | 0.424 | > 0.050 | 0.885 | 0.388 | 0.623 | > 0.050 |
 335 | Cyto | < 0.500 | 0.850 | 0.965 | > 0.050 | 0.778 | 0.664 | 0.451 | > 0.050 |
 391 | Trans | 1.000 | 0.025 | 0.000 | > 0.050 | 1.000 | 0.000 | 1.000 | S |
 404 | Extr | 1.000 | 0.434 | 0.268 | > 0.050 | 0.911 | 0.271 | 0.621 | > 0.050 |
Or83c1 | |||||||||
 9 | Cyto | 0.764 | 0.411 | 0.155 | > 0.050 | 0.975 | 0.133 | 0.712 | > 0.050 |
 99 | Cyto | 1.000 | 0.075 | 0.004 | 0.026 | 1.000 | 0.001 | 0.999 | > 0.050 |
 230 | Cyto | 1.000 | 0.088 | 0.145 | > 0.050 | 0.999 | 0.121 | 0.973 | P, R, I |
 236 | Cyto | 1.000 | 0.136 | 0.105 | > 0.050 | 1.000 | 0.131 | 0.972 | H |
 362 | Trans | 0.536 | 0.451 | 0.136 | > 0.050 | 0.976 | 0.151 | 0.727 | > 0.050 |
 386 | Extr | 0.999 | 0.330 | 0.051 | > 0.050 | 0.996 | 0.033 | 0.971 | H |
 387 | Extr | 1.000 | 0.089 | 0.024 | > 0.050 | 1.000 | 0.036 | 0.992 | > 0.050 |
 391 | Extr | 0.965 | 0.386 | 0.070 | > 0.050 | 0.986 | 0.066 | 0.926 | > 0.050 |
Or83c2 | |||||||||
 7 | Cyto | 0.712 | 0.459 | 0.203 | > 0.050 | 0.972 | 0.229 | 0.828 | > 0.050 |
 21 | Cyto | < 0.500 | 0.459 | 0.285 | > 0.050 | 0.959 | 0.064 | 0.794 | > 0.050 |
 43 | Trans | 1.000 | 0.007 | 0.003 | 0.018 | 1.000 | 0.005 | 0.999 | C |
 92 | Cyto | 0.773 | 0.572 | 0.518 | > 0.050 | 0.855 | 0.000 | 0.644 | C, RP |
 178 | Extr | < 0.500 | 0.478 | 0.271 | > 0.050 | 0.720 | 0.029 | 0.701 | > 0.050 |
 187 | Trans | 0.957 | 0.228 | 0.064 | 0.019 | 0.998 | 0.085 | 0.947 | > 0.050 |
 238 | Cyto | 1.000 | 0.496 | 0.205 | > 0.050 | 0.986 | 0.047 | 0.930 | > 0.050 |
 284 | Trans | 0.845 | 0.176 | 0.063 | > 0.050 | 0.992 | 0.07 | 0.984 | > 0.050 |