Fig. 2From: Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebratesSequence alignment of FADS1 and FADS2 amino acid sequences. Orange boxes correspond to the conserved histidine boxes, the yellow box indicates residues proposed to be involved in substrate specificity [27], and blue boxes indicate residues replaced in rat FADS2 Δ6 desaturase to obtain Δ5 activity [27]. The heme binding motif HPGG is also shownBack to article page