Fig. 3From: Origin and diversification of the plasminogen activation system among chordatesPresence of plasminogen activation system members and related paralogues among the chordate species investigated. Squares indicate absence (light grey), presence (dark grey) and duplication (black) of the different orthologues. Dashed-lines (---) indicate non-canonical protein domain composition. Approximate divergence time in million years ago (mya) was collected from [54,55,56,57,58,59]. PLG (plasminogen), HGF (hepatocyte growth factor), MST-1 (macrophage stimulating 1), HABP2 (hyaluronan binding protein 2), HGFAC (hepatocyte growth factor activator), tPA (tissue-type plasminogen activator) and uPA (urokinase-type plasminogen activator), VTN (vitronectin), uPAR (urokinase-typle plasminogen activator receptor), LU (Ly6/LU domain)Back to article page