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Table 3 Estimated inactivation times, in millions of years, for select branches where the ODAM gene accumulated its first inactivating mutation

From: Odontogenic ameloblast-associated (ODAM) is inactivated in toothless/enamelless placental mammals and toothed whales

Branch

CF1

CF2

Mean inactivation date

ωp = 1.0 (fixed)

ωp = 1.0446 (estimated)

ωp = 1.0 (fixed)

ωp = 1.106 (estimated)

1 syn rate

2 syn rates

1 syn rate

2 syn rates

1 syn rate

2 syn rates

1 syn rate

2 syn rates

Orycteropus

58.99

53.76

54.24

48.26

65.8

62.2

53.91

47.89

55.63

Dasypus

41.96

40.63

38.59

36.24

45.45a

45.45 a

38.7

36.38

40.43

Stem Chlamyphoridae

45.45a

45.45a

44.93

44.73

45.45a

45.45 a

45.43

45.42

45.29

Physeter

26.07

24.04

23.97

21.56

32.43a

32.43a

26.95

25.14

26.57

Stem Pholidota

65.39

62.60

61.16

57.34

73.04

72.93

62.16

58.55

64.15

Callithrix

14.03

12.41

12.90

11.17

15.81

14.47

12.95

11.23

13.12

  1. aEstimated inactivation age constrained by divergence time on timetree
  2. Abbreviations: CF1 codon frequency model 1, CF2 codon frequency model 2, syn synonymous, ωp =dN/dS for pseudogenic branch category