Fig. 6
From: A large close relative of C. elegans is slow-developing but not long-lived
Intersection of relevant life history trait phenotypes in C. elegans protein-coding genes. In C. elegans, many genes that can increase body length, slow development, extend lifespan, or reduce fecundity when defective do not also promote correlated changes in life history traits often associated with increased body size. Matrix layout plot shows intersections of C. elegans genes among four WormBase phenotype terms [48] (“long,” “extended life span,” “reduced brood size,” “slow growth”; plot generated in R with the UpSetR package [86]). Most genes intersect with only one phenotype (the first, second, fourth, and sixth columns from the left), whereas only four genes display all four phenotypes. Most protein-coding genes in C. elegans do not have any reported phenotypes (also see analysis in [49]). See methods for more details.