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Table 3 Positively selected genes associated with mitochondrial biogenesis identified in a meta-analysis across three evolutionary clades with exceptional short or long lifespans

From: Analysis of the coding sequences of clownfish reveals molecular convergence in the evolution of lifespan

Gene symbol

p-value

FDRd

Clownfish LCAa

Nothobranchius b

Mole-ratb

Combinedc

MTERF1

7.34E-03

1.25E-03

2.57E-02

3.12E-05

4.01E-04

RARS2

1.82E-03

1.18E-02

NAe

2.52E-04

2.43E-03

MRPL30

2.55E-02

1.00E+ 00

9.59E-03

2.28E-03

7.98E-03

FASTKD2

1.77E-04

1.56E-01

1.00E+ 00

3.16E-04

2.43E-03

FASTKD5

NAe

1.39E-03

8.25E-01

8.89E-03

2.44E-02

TFB2M

NAe

4.34E-04

6.91E-01

2.73E-03

9.15E-03

NDUFA9

NAe

8.31E-02

6.90E-03

4.85E-03

1.56E-02

  1. a LCA – last common ancestors
  2. b These p-values resulted from meta-analysis using Fisher’s method of 3 ancestral Nothobranchius and 11 examined mole-rat branches on which lifespan changed considerably
  3. c This p-value results from a meta-analysis of the three p-values in the left columns using Fisher’s method
  4. d FDR – false discovery rate (adjusted p-value for multiple testing)
  5. e NA – no p-value calculated since the gene could not be tested in the respective context