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Table 2 Differentially expressed candidate color genes in our transcriptome. Parentheses in the gene symbol column indicate the number of transcripts that mapped to a particular gene. The pathway column indicates what color or pattern production pathway this gene is a part of

From: Variation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus

Gene symbol

q value

Pathway

Citation

adam17 (2)

0.0163; 0.0469

Melanocyte development

[20]

arfgap1 (2)

0.00362; 0.0267

Putative guanine synthesis in iridophores

[26]

arfgap3 (4)

0.00739; 0.0000123; 0.00132; 0.0282

Putative guanine synthesis in iridophores

[26]

airc

0.0126

Guanine synthesis

[27]

atic

0.0447

Guanine synthesis in iridophores

[26]

atox1

0.00124

Melanogenesis

[28]

atp12a

0.0296

Melanogenesis

[29]

bbs2

0.0300

Melanosome transport

[30]

bbs5

0.0447

Melanosome transport

[30]

bmpr1b

0.0118

Inhibits melanogenesis

[31]

brca1

0.0455

Alters pigmentation, produces piebald appearances in mice

[32, 33]

ctr9

0.0280

Melanocyte assembly

[34, 35]

dera

 

Guanine synthesis in iridophores

[26]

dio2 (3)

0.0338; 0.0256; 0.000866

Thyroid hormone pathways, tenuous

[36]

dtnbp1 (2)

0.00120; 0.0456

Melanosome biogenesis

[37]

ednrb (2)

0.0035; 0.0005

Guanine synthesis in iridophores, melanoblast migration

[26, 38]

egfr (2)

0.0197; 0.000566

Melanocyte pigmentation and differentiation

[39]

fbxw4 (2)

0.00268; 0.0183

Melanophore organization

[40, 41]

gart

0.0000494

Purine synthesis, affecting iridophores, xanthophores, and melanophores

[42]

gas1 (2)

0.0264; 0.0191

Guanine synthesis in iridophores

[26]

gne (2)

0.00571; 0.0361

Sialic acid pathway

[43]

hps3

0.0202

Melanosome biogenesis

[18]

itgb1 (2)

0.0191; 0.0469

Guanine synthesis in iridophores

[26]

lef1

0.0190

Melanocyte differentiation and development, melanogenesis

[44]

leo1

0.0000381

Melanocyte assembly

[45]

mitf

0.0466

Melanocyte regulation

[46]

mlph

0.00568

Melanosome transport

[47]

mthfd1

0.0430

Purine synthesis

[48]

mreg

0.0156

Melanosome transport

[49]

notch1 (3)

0.00681; 0.0139; 0.0487

Melanocyte production

[50, 51]

prtfdc1

0.00000672

Guanine synthesis

[26]

qdpr

0.0372

Guanine and Pteridine synthesis

[52, 53]

qnr-71 (2)

0.0316; 0.0262

Melanosomal protein

[54, 55]

rab3d

0.0321

Putative guanine synthesis in iridophores

[26]

rab7a

0.0319

Putative guanine synthesis in iridophores

[26]

rabggta

0.000864

Guanine synthesis

[56]

scarb2

0.0329

Putative guanine synthesis in iridophores

[26]

shroom2

0.0142

Pigment accumulation

[57, 58]

sox9

0.0228

Melanin production

[59]

tbx15

0.00838

Pigmentation boundaries

[60]

tyrp1

0.0200

Melanogenesis

[61]

xdh (2)

0.0346; 0.0384

Pteridine synthesis

[62]