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Fig. 6 | BMC Evolutionary Biology

Fig. 6

From: The first identification of complete Eph-ephrin signalling in ctenophores and sponges reveals a role for neofunctionalization in the emergence of signalling domains

Fig. 6

Reconstruction of the proposed evolution of Eph-ephrin receptor-ligand pairs. A simplified phylogenetic tree of the evolutionary relationship of relevant eukaryotes; not all eukaryotic lineages are shown. Prokaryotes are shown basal to eukaryotes. A coloured circle against a lineage name denotes the presence of a given gene family in that lineage; a question mark denotes uncertainty. An orange dot in the centre of brown circles representing monodomain cupredoxins denotes copper binding ability

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