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Fig. 3 | BMC Evolutionary Biology

Fig. 3

From: On estimating evolutionary probabilities of population variants

Fig. 3

Relationship of protein evolutionary rate with eForbs classification error (ΔeForb). a Distribution of ΔeForb for 18,391 human proteins. b Proteins with higher evolutionary rates, on average, have higher ΔeForb. c The distribution of branch-length distances (tree difference) between the standard timetree and inferred RelTime trees. d Relationship between protein evolutionary rate and tree distance. For (b) and (d), the gray area corresponds to the standard error of the mean interval. Protein evolutionary rate is the ratio of sum of Maximum Likelihood estimates of branch lengths and the total evolutionary time in the tree of 46 species. Proteins with evolution rate > 2×10− 3 substitutions per site per million years were combined into one bin, shown as the rightmost points in panels (b) and (d)

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