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Fig. 7 | BMC Evolutionary Biology

Fig. 7

From: Adapting the engine to the fuel: mutator populations can reduce the mutational load by reorganizing their genome structure

Fig. 7

Metabolic error of the populations (top curves) and metabolic error of the ancestral lineages (bottom curves), averaged per WT and per 1000 generations. a) Metabolic error of the controls populations and lineages. Both the average metabolic error and the metabolic error of the ancestral lineages decrease in all populations. b) Metabolic error of the mutator populations and lineages. While the metabolic error of the ancestral lineage decreases (after the initial increase), the average error of all populations typically increases beyond their initial value at generation 300,000 and goes on increasing even while the metabolic error of the lineage started decreasing: Mutators lineages improve their fitness at the expense of the general population

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