Fig. 6

Anticipation can entail polymorphism or a single lineage that switches between two metabolic modes. a Two lineages occupy different niches on the growth vs. yield trade-off WT02#01 diverges into a slow growing lineage (yellow lineage, average death rate ±0.015) and a faster growing lineage with elevated death rates (blue lineages, average death rate ±0.048), together anticipating the serial transfer protocol. b A single lineage anticipates the daily cycle by trimming and tuning the gene regulatory network. On the left the ancestral GRN, protein allocation dynamics, and resource concentrations are displayed over the course of 1 day. Next, after 400 days, all three independent simulations of WT07 are shown to have evolved to anticipate as a single lineage with two metabolic modes