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Table 1 Types of mutations and their probabilities in WT evolution and serial transfer protocol (STP)

From: Trusting the hand that feeds: microbes evolve to anticipate a serial transfer protocol as individuals or collectives

Mutation

Description

Prob (WT evolution)

Prob (STP)

Duplication

A stretch of 1 or more genes is duplicated in tandem

0.005

0.0015

Deletion

A stretch of 1 or more genes is deleted

0.005

0.0015

Inversion

A stretch of 1 or more genes is inverted in order

0.005

0.0015

Translocation

A stretch of 1 or more genes is moved to a random location

0.005

0.0015

(stretch length)

Geometrically distributed with p = 0.3

-

-

Gene discovery

Per time-step probability of discovering a new (randomly parameterised) gene.

0.0002

(disabled)

HGT

Per time-step probability of copying a gene from a cell closeby

0.002

(disabled)

Point mutation

Per gene per generation probability of modifying a single parameter of a gene (promoter strength, Michaelis Menten constants)

0.005

0.0015

Regulatory mutation

Per gene per generation probability of (partially) modifying the upstream binary operator sequence of a gene

0.005

0.0015