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Fig. 7 | BMC Evolutionary Biology

Fig. 7

From: Natriuretic peptides appeared after their receptors in vertebrates

Fig. 7

a Superposition of the three-dimensional structure of the human natriuretic peptide with the ten peptides found in non-vertebrate animals. The human natriuretic peptide is shown in yellow. b Model of binding of the five peptides from non-vertebrate animals in a binding pocket of the human NPR3 receptor different from that occupied by of human natriuretic peptides. The receptor is represented in green, the natriuretic peptide NPPA in brown. The five peptides from each of the five non vertebrate species are represented respectively in red, blue, violet, pink and azure. c Model of binding of the five peptides from non-vertebrate animals in the same binding pocket of the human NPR3 receptor as that occupied by the human natriuretic peptides. The receptor is represented in green, the natriuretic peptide NPPA in brown. The five peptides from each of the five non-vertebrate species are respectively represented in violet, yellow, beige, pink and orange

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