Fig. 1

Phylogenetic tree of the TLR5 gene. Maximum likelihood (ML) method and the GTR + G model of nucleotide substitution were used to obtain the TLR5 phylogenetic tree, which was then constrained to better recover the mammalian relationships according to the currently accepted mammalian species tree [14]. Branch lengths in substitutions per codon were calculated under the CODEML M0 model [15]. Highlighted in bold and colored are the foreground branches used in branch model and RELAX analyses: Chiroptera in dark green, Lagomorpha in red, Rodentia in green and Carnivora in black; in dashed bold are the Carnivora tips, excluded from the Carnivora ancestral analysis in RELAX. Colored are also the Euungulate (light blue) and Primata (yellow) branches