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Fig. 1 | BMC Evolutionary Biology

Fig. 1

From: A single mutation in the ACTR8 gene associated with lineage-specific expression in primates

Fig. 1

Structural analysis of the ACTR8 gene and AluSz6 integration analysis in various primates. a Isotig is a putative transcript from the transcriptome study of the crab-eating monkey. Dotted boxes represent the putative exon and the Alu-derived exon. Open and closed boxes represent the UTR region and ORF region, respectively. In all primates, the antisense-oriented AluSz6 element is located between exon 7 and exon 8 of the ACTR8 gene. Thick arrows indicate the location of the genomic PCR primer. This figure is schematic and not to scale. b Genomic PCR amplification for AluSz6 integration analysis in the ACTR8 gene using various primate samples. M indicates the size marker. Primate DNA samples are abbreviated as follows: HU: human (Homo sapiens); CH: chimpanzee (Pan troglodytes); GO: gorilla (Gorilla gorilla); RH: rhesus monkey (Macaca mulatta); CR: crab-eating monkey (Macaca fascicularis); AGM: African green monkey (Chlorocebus aethiops); MAR: Marmoset (Callithrix jacchus); SQ: squirrel monkey (Saimiri sciureus); RTL: ring-tailed lemur (Lemur catta)

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