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Fig. 11 | BMC Evolutionary Biology

Fig. 11

From: Investigating cellular and molecular mechanisms of neurogenesis in Capitella teleta sheds light on the ancestor of Annelida

Fig. 11

Models of C. teleta brain and trunk neurogenesis. a A hypothetical GRN underlying brain neurogenesis. There is a transition from apical proliferative EdU+ cells to more basal differentiating neural cells that are spatially segregated from each other. Different combinations of transcription factors are expressed along these different spatial domains in the head as indicated. b, b′ A hypothetical GRN underlying VNC neurogenesis showing different EdU labeled cell populations with differential expression of transcription factors in the surface versus subsurface cells in the trunk neuroectoderm along the apical-basal axis b and along the dorsoventral axis b′. fg, foregut; A: anterior; P: posterior; D: dorsal; V: ventral. Dashed lines indicate the demarcations between the different spatial domains

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