Fig. 1From: Frequent birth-and-death events throughout perforin-1 evolutionVertebrate perforin-1 genes. a phylogenetic relationships between annotated species. For each species, the number of putatively functional (N) and pseudogenized (Ψ) genes is shown. b representative alignment of annotated perforin-1 amino acid sequences. Key residues in each motif are highlighted with an arrow. Numbers correspond to the human protein. Hsap, Homo sapiens; Ecab, Equus caballus; Bbon, Balaenoptera bonaerensis; Ttru, Tursiops truncatus; Eeur, Erinaceus europaeus; Lafr, Loxodonta africana, Dnov, Dasypus novemcinctus; Pcin, Phascolarctos cinereus; Oana, Ornithorhynchus anatinus; Acar, Anolis carolinensis; Cpic, Chrysemys picta; Ggal, Gallus gallus; Xtro, Xenopus tropicalis; Olat, Oryzias latipes; Amex, Astyanax mexicanus; Drer, Danio rerio; Cpla, Chiloscyllium plagiosumBack to article page