Figure 4
From: Conservation and divergence of ADAM family proteins in the Xenopus genome
Sequence comparison of mammalian and Xenopus ADAM15. Sequence alignment of human, chimpanzee (PANTR), canine (CANFA), bovine (BOVIN), mouse, rat, X. laevis (XENLA) and X. tropicalis ADAM15 was generated using ClustalX. Domain organization of ADAM15 is shown with insets displaying alignments of the zinc-binding motif (the Gln in Xenopus ADAM15 is highlighted in bold and underscored), the RGD integrin-binding sites, and the conserved proline residues in the cytoplasmic tail. Conserved residues are highlighted in grey. See Figure 1 legend for abbreviations of domain names and Additional File 2 for a complete sequence alignment that also includes zebrafish ADAM15 proteins.