Table 2 Selectivity filters and NPA-boxes

MIPA

CcMIPA1;1

H

M

M

R

NPM

NPA

At TIP2;1

H

I

G

R

NPA

NPA

water [58], urea [59], ammonia [60]

MIPB

OlMIPB1;1

Y

L

G

R

NPS

NAA

OrMIPB1;1

Y

F

G

R

NPS

NAA

GLA _Llac

Y

V

P

R

NPA

NPA

water, glycerol [25]

MIPC

MpMIPC1;1

L

C

G

V

NPT

NPA

MrMIPC1;1

I

T

G

V

NPT

NPA

OtMIPC1;1

V

M

C

P

NPV

NPS

Zm SIP2;1 ^c

S

H

G

S

NPL

NPA

none [61]

Os NIP2;1 ^c

G

S

G

R

NPA

NPA

silicic acid [62], arsenite, antimonite [63]

MIPD

VcMIPD1;1

N

A

A

R

NPA

NPA

CcMIPD1;1

N

A

A

R

NPA

NPA

CnMIPD1;1

N

A

A

R

NPA

NPA

Cr MIPD1;1

N

A

A

R

NPA

NPA

glycerol [15]

VcMIPD2;1

T

L

S

R

NPA

NPA

CrMIPD2;1

T

L

S

R

NPL

NPA

CcMIPD3;1

S

T

A

R

NPA

NPA

VcMIPD4;1

N

A

T

H

NPT

NPA

Os TIP4;1

T

T

A

R

NPA

NPA

water, glycerol [29]

MIPE

OrMIPE1;1

F

H

C

R

NPA

NPA

CnMIPE1;1

F

H

C

R

NPA

NPA

CnMIPE1;2

A

H

C

R

NAA

NPT

CnMIPE1;3

F

H

C

R

NPA

NPA

Hs AQP5

F

H

C

R

NPA

NPA

water [34]

PIP

CcPIP4;1

F

H

C

R

NPA

NPA

CcPIP4;2

F

H

C

R

NPA

NPA

At PIP2;3

F

H

T

R

NPA

NPA

water [64]

GIP

PbcvMT325GIP1;1

F

V

I

R

NPA

NPA

CcGIP1;1

F

L

N

R

NPA

NPA

CnGIP1;1

F

I

I

R

NPA

NPA

Pp GIP1;1

F

V

P

R

NPA

NPA

glycerol [24]