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Table 1 Paralogous pairs with divergent functions

From: Horizontal and vertical growth of S. cerevisiaemetabolic network

Paralogous pairs

Paralogy definition

DiceM coefficient

Correlation of the expression levels

Enzyme 1

Enzyme 2

Need

Ens

Wap

YBP

KEGG

Pearson coeff.

P value

YBR149W

YHR104W

Y

Y

N

0

N/A

0.68

2.2-16

YDL080C

YDR380W

Y

Y

Y

0.67

0

0.08

0.033

YDL246C

YLR070C

Y

Y

Y

N/A

0

N/A

N/A

YDR147W

YLR133W

Y

Y

N

0

0.5

0.09

0.02

YDR380W

YGR087C

Y

Y

Y

0.54

0

-0.07

0.065

YDR380W

YLR044C

Y

Y

Y

0.54

0

0.08

0.047

YDR380W

YLR134W

Y

Y

Y

0.54

0

0.01

0.76

YDR399W

YJR133W

Y

Y

Y

0

N/A

0.25

7.6-11

YHR123W

YNL130C

Y

Y

Y

0

0

0.50

2.2-16

YJR159W

YLR070C

Y

Y

Y

N/A

0

0.38

2.2-16

  1. Only pairs identified as paralogs by at least by two paralogy definitions (Need: sequence identity above 30%; Ens: derived from the Ensembl database; Wap: listed by Wapinski et al. [13] ) and with a DiceM coefficient equal to 1 in at least one metabolic network are shown. The complete set of data is shown in Additional file 2.
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BMC Ecology and Evolution

ISSN: 2730-7182

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