Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

Table 2 Identification of the domain location of each positively selected site

Number of sites under positive selection identified in each domain of gene
Gene	No. of species	Total no. of sites^a	Domains^b
			Signal	LRR-NT	LRR	LRR-CT	Transmembrane	TIR
TLR1	17	2	---	---	2	---	---	---
TLR2	23	6	1	---	3	---	1	1
TLR3	20	9	3	---	3	---	1	2
TLR4	19	22	---	---	19	1	1	1
TLR5	17	7	1	---	3	---	---	3
TLR6	20	3	---	---	---	---	2	1
TLR7	21	7	---	---	7	---	---	---
TLR8	18	26	---	1	25	---	---	---
TLR9	21	4	---	---	4	---	---	---
TLR10	13	7	---	---	5	1	---	1

ISSN: 2730-7182