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Table 1 Summary of previous molecular divergence estimates

From: Integration of molecules and new fossils supports a Triassic origin for Lepidosauria (lizards, snakes, and tuatara)

Analysis

Material

No. of squamate taxa

Dating software and/or method

Age crown Lepidosauria

Age crown Squamata

Albert et al. [38]

mtDNA (13 genes)

27

r8s, Penalized Likelihood

289±5

281

Albert et al. [38]

mtDNA (13 genes)

27

“Multidivtime”, Bayesian autocorrelated clock

272±20

259

Alfaro et al. [3]

nDNA: RAG-1

35

BEAST, Bayesian uncorrelated lognormal clock

246 (208-275)

mid TR - mid JU

Gorr et al. [40]

α haemoglobin chains

3 | 6

Strict clock (least-squares regression)

233

n/a

Gorr et al. [40]

β haemoglobin chains

9

Strict clock (least-squares regression)

226

~194

Hipsley et al. [42]

mtDNA and nDNA (5 genes)

40 1

TreeTime, Bayesian uncorrelated lognormal clock

238±10

n/a

Hugall et al. [36]

nDNA: RAG-1

36

r8s, Penalized Likelihood

250-268±12 2

171-190* ±14

Hugall et al. [36]

nDNA: RAG-1, translated

36

r8s, Penalized Likelihood

261-275±17 2

184-201* ±19

Janke et al. [48]

mtDNA

2

Strict clock (after pruning of taxa)

n/a

294 3

Kumar and Hedges [35]

Amino acid sequences (5 genes)

?

Strict clock (after pruning of heterogeneous sequences)

276±54.4

n/a

Kumazawa [37]

mtDNA

24

“Multidivtime”, Bayesian autocorrelated clock

~260-290

~215-255

Mulcahy et al. [43]

mtDNA and nDNA (RAG-1)

64

BEAST, Bayesian uncorrelated lognormal clock

~233 (223-243)

180 (160-198)

Mulcahy et al. [43]

mtDNA and nDNA (RAG-1)

64

r8s, Penalized Likelihood

~275 (na)

191.8 (186-194)

Okajima & Kumazawa [49]

mtDNA

22

“Multidivtime”, Bayesian autocorrelated clock

n/a

240 (220-260)

Pyron [39]

nDNA: RAG-1 4

44

BEAST, Bayesian uncorrelated lognormal clock

236 (212-253)

189 (163-213)

Pyron [39]

nDNA: RAG-1 5

44

BEAST, Bayesian uncorrelated lognormal clock

265 (240-290)

208 (179-234)

Shen et al. [50]

mtDNA and nDNA

5

“Multidivtime”, Bayesian autocorrelated clock

n/a

205 (180-228)

Vidal and Hedges [51]

nDNA: C-mos, RAG-1

19

“Multidivtime”, Bayesian autocorrelated clock

< 251

240 (221-251)

Wiens et al. [41]

nDNA: RAG-1 6

261 7

r8s, Penalized Likelihood

227 8

179 ±5.5

  1. Annotations: 1 focused on lacertids, 2 range of four different estimates provided by varying the number of calibration points, 3Sphenodon was not included amongst the taxa therefore the estimate better corresponds to one for Lepidosauromorpha, 4 four fossil calibrations from Müller and Reisz [52], 5 five fossil calibrations from Hugall et al. [36], 6 supertree approach, 7 focused on taxa with a snake-like bodyform, 8 used as fixed calibration point. Abbreviations: JU Jurassic, TR Triassic.