Figure 1From: Generation of divergent uroplakin tetraspanins and their partners during vertebrate evolution: identification of novel uroplakinsClustering of new UPK members. Clustering of UPK2b, UPK3c and UPK3d in mixed DNA/protein trees showing the evolutionary relationships between UPKs. (A) Tetraspanin uroplakins, and (B) UPK2/3 uroplakins. The major groups of uroplakins are indicated by vertical lines in the figure. Separate protein and DNA parsimony, maximum likelihood and Bayesian phylogenetic trees are included in Additional file 3: Figure S3 and Additional file 4: Figure S4. Red rectangles BP (Bayesian posterior) >0.99; Blue rectangles BPā>ā0.75. Asterisks represent statistically significant (pā<ā0.05) branches where dN/dS ratios are significantly greater than 1.0. The large asterisks mark deep branches and the small asterisks mark more terminal branches. The blue asterisks refer to branches where dN/dSā>ā1.0 in the common ancestor of mammals.Back to article page