Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic Killifish (Fundulus heteroclitus)

Table 6 Single locus F _ST values demonstrating high differentiation among population pairs

	Population comparison
Locus	BI/NBH	FLAX/BP	SH/NWK	KC/ER
Aryl hydrocarbon receptor 1_1530	0.48393	0.15677	−0.00349	0.12191
Aryl hydrocarbon receptor 1_161	0.26498	0.00028	0.00929	N/A
Aryl hydrocarbon receptor 1_2289	0.21749	N/A	−0.00376	N/A
Aryl hydrocarbon receptor 1_948	0.35061	−0.0137	−0.01388	N/A
Aryl hydrocarbon receptor 2_1929	0.25477	0.1825	0.04692	0.19729
Aryl hydrocarbon receptor 2_792	0.36916	N/A	0.00417	N/A
Cathepsin F_653	0.18941	−0.0137	−0.01271	0.03401
Cathepsin Z_624	0.22978	0.04241	−0.00759	−0.00325
Cytochrome P450 1A_2140	0.37453	0.3733	0.20304	0.70083
Cytochrome P450 3A_1166	0.51614	−0.01332	−0.00179	−0.01449
Hepcidin2_399	0.14131	0.06457	0.00719	0.04197
Heat shock protein 90_775	0.09438	N/A	0.02932	0.12676
NADH ubiquinone oxidoreductase MLRQ subunit_363	0.32115	−0.01268	0.12679	−0.01516
Myosin regulatory light chain 3_372	0.11663	−0.00843	−0.01529	0.0674
NADH dehydrogenase subunit 4_347	0.0137	N/A	0.24148	N/A
NADH dehydrogenase subunit 4_586	0.01315	N/A	0.13504	0.01408
NADH dehydrogenase subunit 4_669	0.01259	N/A	0.25714	N/A
NADH dehydrogenase subunit 6_787	0.01486	N/A	0.26028	N/A
Serine protease inhibitor_938	0.00078	N/A	0.03176	0.10229
TBT binding protein_635	0.10673	−0.00786	−0.00228	N/A
Thioredoxin_582	0.19931	0.01625	−0.00785	0.1248

F_ST values for highly differentiated loci across all four DLC-sensitive/-tolerant population pairs. F_STs were calculated using the locus by locus AMOVA function in Arlequin v. 3.5. Values exceeding an F_ST threshold of 0.1 are noted in bold and are significant at p < 0.05. Comparisons that were not made because the markers were monomorphic in some populations are noted as N/A. BI = Block Island, NBH = New Bedford Harbor, Flax = Flax Pond, BP = Bridgeport, SH = Sandy Hook, NWK = Newark, KC = Kings Creek, and ER = Elizabeth River.

ISSN: 2730-7182