Figure 2From: Post-duplication charge evolution of phosphoglucose isomerases in teleost fishes through weak selection on many amino acid sitesCurrent states and inferred evolutionary process of electric charge change in PGI isoforms. (A) Maximum likelihood tree of Pgi genes in ray-finned fishes inferred by BASEML [34] with a known phylogeny [18]. Numbers indicate estimated pI. Arrow denotes a gene duplication event. (B) Amino acid sites that differ by the presence or absence of hydrophilic charged residues between current PGI-1 and PGI-2. Positively charged residues are blue; negatively charged residues, red; other residues, light gray. The numbers above refer to the amino acid positions of PGI [33]. The stars below indicate sites located on the molecular surface. (C) Inferred charge-changing substitution events mapped over the PGI phylogeny. Orange and brown bars denote upward and downward charge changes, respectively.Back to article page