Figure 1From: Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial generaOrganization of the mcyABC gene cluster (A). Adenylation domains investigated in the present study are indicated in red and green. The relative positions of primers (arrows) are shown. Genus-specific mcyB and mcyC primers are listed in Table 8. (B) The structure of microcystin-LR. Amino acid residues activated by the adenylation domains of McyB1 and McyC are indicated by red and green, respectively. Mdha is N-methyl-dehydroalanine, D-MeAsp is 3-methyl-aspartic acid and Adda is 3-amino-9-methoxy-2,6,8,-trimethyl-10-phenyl-4,6-decandienoic acid.Back to article page