Protein evolution in deep sea bacteria: an analysis of amino acids substitution rates

Table 2 COG categories enriched with PS genes in KT99 and SS9

Functional Categories	COGs	KT99	tot	p-value	SS9	tot	p-value
Energy production and conversion	C	5	149	0.214	12	125	0.482
Cell cycle control, cell division, chromosome partitioning	D	1	28	0.175	2	23	0.407
Amino acid transport and metabolism	E	7	173	0.093	22	200	0.261
Nucleotide transport and metabolism	F	4	48	*0.009*	10	60	*0.032*
Carbohydrate transport and metabolism	G	1	50	0.396	9	91	0.424
Coenzyme transport and metabolism	H	2	114	0.606	4	107	0.987
Lipid transport and metabolism	I	0	82	-	6	65	0.476
Translation, ribosomal structure and biogenesis	J	5	124	0.117	9	125	0.817
Transcription	K	0	126	-	10	136	0.816
Replication, recombination and repair	L	3	107	0.330	5	100	0.945
Cell wall/membrane/envelope biogenesis	M	4	106	0.158	16	113	0.050
Cell motility	N	1	73	0.596	9	75	0.210
Posttranslational modification, protein turnover, chaperones	O	2	111	0.587	10	102	0.441
Inorganic ion transport and metabolism	P	4	72	*0.044*	16	107	*0.033*
Secondary metabolites biosynthesis, transport and catabolism	Q	0	34	-	1	28	0.786
General function prediction only	R	4	209	0.683	29	217	0.035
Function unknown	S	19	659	0.319	52	577	0.789
Signal transduction mechanisms	T	0	105	-	11	116	0.494
Intracellular trafficking, secretion, and vesicular transport	U	2	74	0.325	13	81	0.027
Defense mechanisms	V	3	25	0.004	2	36	0.713
Total Orthologs		67	2469		213	2484

Columns represent respectively: functional classes, COG codes, number of PS genes for each category, total number of orthologous genes for each category and p-value calculated using hypergeometric distribution for KT99 (columns 3, 4, 5) and SS9 (columns 6, 7, 8). In bold are highlighted significant values (p = 0.05) and the italicsindicate classes enriched in both bacteria.

ISSN: 2730-7182