Anc | Treatment | Line | aMidpoint genotypes | bTotal | aEndpoint genotypes | bTotal | cCI | dAdap mut |
---|
anc | Control | 1 |
788
| 10/10 |
788,1611, 563
| 5/9 | n, Y | 5 |
| | | | |
788,1611, 587
| 2/9 | | |
| | | | | 788,1611, 576 | 2/9 | | |
anc | Benign | 1 |
788
| 2/10 |
1611
| 2/10 | Y, Y | 3 |
| | |
1611
| 2/10 |
1611, 563
| 3/10 | | |
| | | 878 | 5/10 |
1611, 593
| 5/10 | | |
| | | 878, 1702 | 1/10 | | | | |
anc | Harsh | 1 | ND | |
3129
| 9/9 | --, n | 1 |
anc788 | Control | 2 | ND | | 181, 1033 | 8/10 | --, y | 3 |
| | | | | 181, 1033, 1216 | 1/10 | | |
| | | | | 181, 1295 | 1/10 | | |
anc788 | Control | 3 | none | 1/10 | 1302 | 1/10 | Y, Y | 3 |
| | | 1302 | 3/10 | 1302, 587 | 6/10 | | |
| | |
1702
| 1/10 | 1302, 593 | 2/10 | | |
| | | 3340 | 4/10 | 1302, 1690 | 1/10 | | |
| | | 3340, 581 | 1/10 | | | | |
anc788 | Benign | 2 | none | 5/9 |
563
| 8/10 | y, y | 3 |
| | |
563
| 2/9 |
1295
| 1/10 | | |
| | |
587
| 1/9 |
181
| 1/10 | | |
| | | 624 | 1/9 | | | | |
anc788 | Benign | 3 | ND | | 563, 2772 | 8/9 | --, n | 2 |
| | | | |
563
| 1/9 | | |
anc788 | Harsh | 2 | ND | | 3129, 2973 | 10/10 | --, n | 2 |
anc788 | Harsh | 3 | none | 2/9 | 3039 | 2/10 | n, n | 2 |
| | | 3039, 1138 | 1/9 | 3039, 2971 | 8/10 | | |
| | | 3039 | 6/9 | | | | |
- a Numbers indicate nucleotide positions that are different from ancestor; rows list the mutational position(s) for a single genotype. ND = not done; Bold = parallel mutations.
- b Total number of genotypes over total number of isolates sequenced.
- c CI status of mid- and endpoint populations; y means that multiple mutually exclusive genotypes are present (i.e., A versus B, or AB versus AC, but NOT A versus AB; the latter condition is simply a selective sweep in progress, not competition between genotypes). Y = strong CI, where multiple isolates of competing mutations were observed; y = weak CI, where only one competing isolate was observed.
- d Number of adaptive mutations in endpoint populations as determined from criteria in Table 3. Data were used for Mann-Whitney U-test of Ho: The number of adaptive mutations sampled in control/benign endpoint populations is similar to the number of adaptive mutations sampled in the harsh populations (i.e., adaptive mutations were not sampled from populations with different distributions of adaptive mutations).